7 Lifestyle Changes to Get Rid of Cold sore for Good Cold sores have no known cure just like a typical cold. Nevertheless, you can make some fundamental lifestyle changes in your life as means of eliminating cord sores in your life. But what are cold sores? They are small blister like pimples that form on the lips mainly caused by the herpes virus. The sores are highly contagious and can be passed by direct body contact or getting touch with infected saliva.