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What should a Botox resistant person do? You may be one of those people who have developed an immunity to Botox injections, or you dislike the idea of constantly getting injected with poison into your face, or possibly you’ve had enough of facing the needle every three or four months just to maintain your look. Many situations may arise where you no longer feel the need to use Botox treatments. Fortunately, there are several alternatives that can be used in place of Botox treatments, from using ointments to surgery. Dr. Michael R. Macdonald can provide a variety of new treatments to help you maintain that youthful appearance.

Topical Preparations

There are many ads presenting a new type of medication that’s supposed to be better than Botox. Often they are not, and most of these ads use photo dramatization and other tactics to make you believe what they want. Most topical treatments cannot deliver as much as Botox does, and if they do, it is temporary. Others are very expensive, almost as expensive as the real thing. It would be advisable to skip these lotions and potions and save yourself a lot of money. If topical products could be better than Botox, wouldn’t everyone go for them?


Myobloc is a toxin used in the treatment of migraine headaches, pediatric urinary incontinence, and cervical dystonia, a painful condition affecting the neck and head, among other medical issues. It is also used in patients who have developed a resistance to Botox. Myobloc can be referred to as botulinum toxin (Botox) type B. However, Myobloc has its own drawback. It has not been approved for cosmetic use. Another concern with using Myobloc is that it’s likely that patients who use it will develop antibodies to other types of toxins. Small doses of Myobloc may be able to prolong its usefulness in cosmetic surgery.


Also referred to as AbobotulinumtoxinA, Dysport is a substance used as a neuromodulator. This means it can block a nerve. While it works the same way that Botox does, they differ in their molecular structure. Dysport is smaller than Botox, and this causes it to spread away from the injection site. This spread is an issue when large volumes of the product are injected, particularly in the forehead. If the spread is excess, it results in temporary heavy eyebrows.

Bellafil (Collagen)

Bellafill is another popular filler that can be used. It’s a semi-permanent mixture of collagen and PMMA microspheres. PMMA microsphere is made from bovine or cow collagen and cannot be absorbed by the body, ensuring the results last for up to five years. Bellafill is normally used for acne scars.

Snip the Muscle

This is an invasive surgical option available for people who are only interested in removing vertical frown lines appearing between the eyebrows. Known as corrugator myectomy, the procedure is focused on partially or completely cutting and removing the muscle, drawing the eyebrows together. Risks include a decrease in sensation in between the forehead and a depression that may appear, which may be filled with a dermal filler. Patients should also be aware that the procedure might cause the face to have an exaggerated, permanently “surprised” look. Unless the muscle is completely removed, the results may be temporary.